Acetyl Hexapeptide-3 (Argireline) – 200mg

The research-grade alternative to injectable neurotoxins. Get straight to the mechanism.

Look, you know what Botox does. It blocks signals, relaxes muscles, and smooths lines. Acetyl Hexapeptide-3, commonly called Argireline, is the peptide that works on the same pathway. This 200mg vial is for researchers who want to study a topical, peptide-based approach to modulating muscle contraction at the source.

Here’s the breakdown without the jargon: It’s a synthetic fragment of the SNAP-25 protein. In the lab, it’s shown to compete for a spot in the SNARE complex—that’s the machinery neurons use to release neurotransmitters like acetylcholine that tell muscles to fire. No release, no contraction. Simpler muscle activity in the model can lead to a reduction in the depth and formation of expression lines. It’s not magic; it’s biochemistry.

We’ve read the same studies you have. The 2002 Blanes-Mira paper called it a synthetic hexapeptide with antiwrinkle activity that mimics botulinum toxin. A 2013 trial on a 10% formulation showed a 30% reduction in wrinkle depth in specific areas after 30 days. Another using it twice daily reported a 27% decrease in periorbital wrinkle depth. The data is there. It suggests a potential to not only relax muscles but also support the skin’s structure by promoting endogenous collagen production and improving hydration—key factors in a resilient dermal matrix.

This is a pure, 200mg research quantity. Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2. Molecular Weight: 888.99 g/mol. It’s shipped in a sterile vial, sealed for integrity. We handle it with the same respect as any precise tool.

Important Protocol: This is a raw material for in vitro (laboratory) research only. It is not for human or animal consumption. It is not a drug, cosmetic, or dietary supplement. You are responsible for knowing and complying with all local, state, and federal regulations regarding the handling of research peptides