Nonapeptide-1 (200mg) | Melanostatine-5 Research Peptide

You’re looking at a serious research tool. PeptideLabsDirect supplies Nonapeptide-1 in its pure, lyophilized form for controlled in-vitro study. This isn’t a casual compound; it’s a precision-engineered 9-amino acid chain (Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val) built to target the melanocortin-1 receptor (MC1R). Think of it as a high-specificity blocker for a key pathway.

The published data is compelling. In laboratory settings, Nonapeptide-1 has demonstrated a potent capacity to inhibit melanin synthesis at the cellular level. It doesn’t just sit on the shelf; it works by binding to the MC1R, disrupting the signal that kicks off the pigment production process. Studies note significant reductions in tyrosinase activity and related proteins in melanocytes after exposure. For researchers focused on melanogenesis mechanisms, hyperpigmentation models, or receptor-level interactions, this peptide provides a direct line of inquiry.

We keep the specs clear because your work demands it. Each vial contains 200mg of >99% purity peptide. Molecular weight is 1206.52 g/mol. You’ll find it under the names Melanostatine or Melanostatine-5. We ship it stable and lyophilized, ready for your lab’s reconstitution protocols.

Key Research Points:

• Primary Action: Potent MC1R antagonist, inhibiting α-MSH binding and downstream signaling.
• Observed In-Vitro Effects: Reduces expression of tyrosinase, TRP-1, TRP-2, and MITF in melanocytes.
• Study Context: Cited in research exploring modulation of pigmentation in cellular and animal models.
• Handling: For research use only in controlled laboratory environments. Not for human or animal consumption.

Our operation is straightforward. We synthesize, test, and ship. Every batch is third-party verified for purity and mass spec. You get the data sheet with your vial. If your protocol requires a high-potency MC1R inhibitor to test hypotheses on pigment regulation or receptor function, this is your material.

Ordering Note: All sales are restricted to verified institutions, licensed professionals, and qualified researchers. You must acknowledge and adhere to our Terms & Conditions regarding the lawful, research-only application of this compound. Orders placed by 12 PM PST ship same day.

Disclaimer: The content on this page is for informational purposes only. Nonapeptide-1 is a